Here's a sample itinerary for a 4-day weekend in late January (easily expanded or compacted as time allows).

Thursday
Afternoon: Arrive Juneau mid-day. After checking into one of Juneau's many comfy accommodations, set the tone for your adventure weekend by heading to the Mendenhall Glacier Recreation Area. Enjoy the exhibits at the visitors' center, then get out there and have some fun – snowshoe or cross-country ski on the lake (rentals available in town), trek across the lake to the glacier face, or walk one of the many trails.
Evening: Dinner and nightlife – choose from one of Juneau's many fine restaurants, then check out open mic night at the historic Alaskan Hotel & Bar.

Friday
Morning: Head up to Eaglecrest Ski Area for a day on the mountain . A paradise for powder lovers, Eaglecrest tends 36 alpine runs and offers tons of ungroomed areas. The Snowsports School's certified instructors will get everyone up and running – whether it's on skis or snowboards.
Evening: Choose another fine restaurant for dinner, then catch a performance at Perseverance Theatre.

Saturday
Morning: It's time to give heli-skiing a try. Check out half-day and full-day packages with Alaska Powder Descents.
Afternoon: On the way back to town, stop by the Alaskan Brewing Company and the Alaska Seafood Company for tours and tastes.
Evening: After dinner, take in a performance by the Juneau Symphony – or show about a gallery walk?

Sunday
Morning: Enjoy a sourdough bagel and locally roasted coffee before a casual stroll through town while you shop for local arts and crafts.
Afternoon: Cross-country ski, skate ski, or snowshoe at the Mendenhall Lake Campground (closed to camping in winter, but open for skiing).
Evening: Catch a flight home while wishing you didn’t have to leave.